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Minds in the Loop

Technology 01 · WBE

Written by the team

Could an emulated human brain improve alignment or preserve human agency?

Whole brain emulation would create digital minds derived from human brains. We assess the claim that those minds would improve alignment or preserve human agency. How exactly they would do that is still unresolved, and so are WBE's feasibility and its welfare implications.

Where we land

Full scorecard

All six ratings are Unclear for now. For four of them, the reason is that the proposal isn't specific enough to assess.

  • Alignment caseUnclearLow confidence
  • Intelligence CurseThe risk that increasingly capable AI reduces the economic and political value of human work and participation, and so weakens human agency. caseUnclearLow confidence
  • Human welfare riskUnclearLow confidence · potentially high severity
  • Artificial-mind welfare and rights riskUnclearLow confidence · potentially high severity
  • Governance riskUnclearLow confidence · potentially high severity
  • Safeguard adequacyUnclearLow confidence

8 milestones on the timeline, none dated yet

How to read the marks
  • From a sourceQuoted word for word from a cited source.
  • Our readThe team's own interpretation.
  • AI-suggestedSuggested by an AI model, set in a dashed outline.
  • UnclearWe don't know yet, and the tag gives the reason.
More on the marks in our methodology

At a glance

The team's read unless marked

What it claims to solve

Both alignment and the Intelligence Curse

How it would help alignment

Potentially value specification, oversight or interpretability.

Strongest case

The team hasn't written the strongest case yet.

Strongest objection

Conventional alignment research may solve the relevant problems sooner.

From the team's scorecard counterarguments.

Artificial minds

Unclear. We haven't found a source that assesses whether an emulation would be conscious or sentient.

Main welfare risks

Consent violations, harms to identity and continuity, copying or exploitation, suffering of digital minds, concentration of power, value lock-in and unsafe deployment.

How it would work

The team's read unless marked

What it claims to solve

From the team’s scope

Both alignment and the Intelligence Curse

The steps it depends on, in order

  1. Brain scanning, functional modeling and simulation become accurate enough.

  2. A human brain is emulated, with legitimate consent and governance arrangements in place.

  3. The emulation is deployed as an AI system, an overseer, a researcher or a contributor.

  4. Its human-derived cognition improves value specification, oversight or institutional decision-making.

  5. Safeguards prevent exploitation, abuses of copying, welfare harms and concentration of power.

Strongest case and objections

The team's read unless marked

For

The strongest case

The team hasn't written the strongest case yet.

Against

The strongest objections

From the team's scorecard: the most credible alternatives and counterarguments.

  1. 01

    Conventional alignment research may solve the relevant problems sooner.

  2. 02

    WBE may end up advancing AI capabilities more than safety.

  3. 03

    Regulatory, moral and technical bottlenecks may keep it from being deployed in time. S02 (Thiergart 2023) points to the regulatory and moral bottlenecks explicitly.

    See Thiergart 2023 (opens in a new tab)

  4. 04

    S13 (Mineault et al. 2025) presents brain emulation as one of several underdeveloped NeuroAI pathways, and makes no case that it's an established safety solution.

    See Mineault et al. 2025 (opens in a new tab)

Artificial minds

The team's read unless marked

Consciousness

Unclear. We haven't found a source that assesses whether an emulation would be conscious or sentient.

Moral status

Unclear. S02 (Thiergart 2023) identifies moral bottlenecks but doesn't set out a framework for moral status or a standard for protecting emulated minds.

See Thiergart 2023 (opens in a new tab)

Identity

Unclear. How an emulated mind relates to the original person isn't addressed in the sources we have.

Welfare

Unclear. The proposal could create digital minds whose welfare is at stake, but no source assesses suffering, consent, copying, confinement, acceleration, deletion or labor conditions.

Welfare and governance risks

The team's read unless marked

Welfare and governance · WBE
Who could be harmed

Emulated minds, if any are created; people whose brains are scanned; users; workers; the wider public; and future generations.

Possible harms

Consent violations, harms to identity and continuity, copying or exploitation, suffering of digital minds, concentration of power, value lock-in and unsafe deployment.

Severity and reversibility

We haven't assessed it yet. It could be high, and hard to reverse if emulations can be copied or modified, or can persist indefinitely.

Detectability and remedies

Unclear. Our sources don't specify any way to detect harms or remedy them.

Control, oversight and exit

Unclear. No governance arrangements have been specified.

Confidence
Low
Basis

S02 (Thiergart 2023) identifies moral and regulatory bottlenecks, and S15 (Drago 2025) describes the risks of concentrated power and of less investment in people. But we don't have enough WBE-specific welfare or governance evidence to tell likely harms from speculative ones.

See Thiergart 2023 (opens in a new tab); Drago 2025 (opens in a new tab)

Milestones

None of the 8 has a date yet, and nothing is mapped at the Actually helping stage. Each row opens the milestone on the timeline.

Full assessment

The full scorecard with the basis for each rating, the scope, the evidence register, the alignment questions and the Intelligence Curse questions.

Show the full assessmentHide the full assessment

The team's read unless marked

Full scorecard

The ratings use the scales in the team’s draft scorecard. If an Unclear risk could be severe, its row also says how severe. “Not claimed” means the proposal doesn’t claim that outcome, so there is no case to grade. We never rate a risk Low just because nobody has studied it, and the cutoffs for the risk ratings aren’t set yet. How we rate

Scorecard · WBERubric v0.1-draft
Scorecard for Whole brain emulation
DimensionRatingConfidenceBasis
Alignment caseCase · AlignmentUnclearUnderspecified proposalLow

S02 (Thiergart 2023) and S13 (Mineault et al. 2025) both name WBE as a possible pathway for alignment, but neither shows how an emulation would solve a specific alignment problem. The evidence we have isn't enough to tell whether WBE is a promising research direction or an intervention that matters for safety.

See Thiergart 2023 (opens in a new tab); Mineault et al. 2025 (opens in a new tab)

Intelligence Curse caseCase · Intelligence CurseUnclearUnderspecified proposalLow

S15 (Drago 2025) describes the risk that powerful actors lose their incentive to invest in people. None of our sources says how WBE would help, or shows that it would counteract that risk. Who would own the scans, the emulations, the compute and the labor they produce is unresolved.

See Drago 2025 (opens in a new tab)

Human welfare riskRiskUnclear, Potentially high severityNo relevant evidence foundLow

Scanned people, users, workers, the wider public and future generations could all be exposed to harm.

More in Welfare and governance risks
Artificial-mind welfare and rights riskRiskUnclear, Potentially high severityNo relevant evidence foundLow

The proposal could create digital minds whose welfare is at stake.

See Thiergart 2023 (opens in a new tab)

More in Artificial minds
Governance riskRiskUnclear, Potentially high severityUnderspecified proposalLow

No governance arrangements have been specified, and the sources we have describe no way to detect or remedy harms.

See Thiergart 2023 (opens in a new tab); Drago 2025 (opens in a new tab)

More in Welfare and governance risks
Safeguard adequacyCaseUnclearUnderspecified proposalLow

The theory of change depends on safeguards against exploitation, abuses of copying, welfare harms and concentration of power.

See Thiergart 2023 (opens in a new tab)

More in Welfare and governance risks

Grading key

CaseStrongModerateWeakUnclearNot claimed
RiskHighMediumLowUnclear
WarningPotentially high severityHow bad an Unclear risk could be. The rating itself stays Unclear.

Main gap in the evidence

Our current sources don't include enough technical, empirical, welfare or governance literature to assess WBE as an intervention for alignment or the Intelligence Curse.

Scope

Scope · WBE
Intervention

A high-fidelity digital emulation of a human brain, which might be used as a human-derived AI system or as an overseer.

Deployment scenario

Research, then deployment if it turns out to be feasible: emulated minds working as trusted AI systems, as overseers or as contributors to alignment research.

Who it affects

Emulated individuals, if any are created; the people whose brains may be scanned; developers and operators; users of AI systems; and society more widely.

Time horizon

Long term. The current evidence doesn't support any defensible near-term date for deployment.

Compared with

Conventional AI alignment methods, including interpretability, evaluations, oversight, control and value learning.

Claims to address

Both alignment and the Intelligence Curse

Evidence register

Each row is one claim, with the sources for and against it, the kind of evidence, its directnessHow close a piece of evidence comes to the scenario being assessed: direct, adjacent or remote., its main limitation and the sources’ independenceWhether the author or funder has a stake in the result..

Evidence register · WBE4 claims
Evidence register for Whole brain emulation
ClaimSupportingContraryEvidence typeDirectnessMain limitationIndependence

WBE could contribute to alignment.

S02S13None in our current sourcesArgument / reviewRemoteNo one has shown that an emulation would be safer, aligned or deployable.Mixed

Regulatory and moral bottlenecks could delay WBE.

S02None in our current sourcesArgumentAdjacentA workshop-level claim, with no policy analysis or empirical test behind it.Unclear

Neuroscience-inspired methods may support safety.

S13None in our current sourcesResearch roadmapRemoteIt doesn't show that WBE in particular improves alignment.Independent

WBE could preserve or distribute human agency.

None in our current sourcesS15ArgumentRemoteNo evidence links WBE to broad ownership, bargaining power or institutional change.Not applicable

The Supporting and Contrary columns list sources by the team’s register IDs. Each ID links to the source’s card in the source database.

The alignment case

The alignment problem it targets

Potentially value specification, oversight or interpretability.

  1. Does the mechanism address that problem, or move it somewhere else?

    Unclear. An emulation could inherit human values, but it could also inherit human biases, conflicts, limitations and governance failures.

  2. Could a more capable AI undermine or get around the benefit?

    Unclear. Nothing we've read tests whether an overseer based on an emulation would stay effective against a more capable AI.

  3. Does it create another agent or decision-maker that would itself need to be aligned or governed?

    Yes, potentially. An emulated mind would itself need moral treatment and governance, and possibly alignment safeguards too.

  4. What's the benefit relative to the comparatorThe alternative a proposal is measured against. Here: conventional AI alignment methods, including interpretability, evaluations, oversight, control and value learning.?

    Unclear. There's no direct comparison with conventional alignment methods to go on.

Rating
UnclearUnderspecified proposal
Confidence
Low
Why: see the Alignment case row in the scorecard

Decisive open question

Which specific alignment failure would a WBE-based system solve better than alignment methods that don't use WBE, and what evidence would show that?

The Intelligence Curse case

The mechanism it claims

Potentially wider ownership of productive AI capacity or of human-derived labor. Our current sources don't specify the mechanism.

  1. Who gains lasting agency or bargaining power?

    Unclear. It could be emulated individuals, biological people, developers or the owners of compute.

  2. Who owns and controls the infrastructure, the data and the returns?

    Unclear. Ownership of the scans, the emulations, the compute and the labor they produce is unresolved.

  3. Does it complement human contributions, delay replacement or deepen dependence?

    Unclear. WBE could expand human-derived capacity, or it could create a new class of digital labor that's open to exploitation.

  4. What's the benefit relative to the comparator?

    Unclear.

Rating
UnclearUnderspecified proposal
Confidence
Low
Why: see the Intelligence Curse case row in the scorecard

Decisive open question

What arrangements for ownership, consent, labor and access to compute would let WBE increase broad human agency without creating a new class of dependent digital workers?

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